Bowelcancer Frame

Colonic Physiology Ursula M. Szmulowicz and Tracy L. Hull The human colon is a high-powered pipe electronic organ, touch on in a massive array of functions, including the absorption of water and electrolytes, the lay aside of unabsorbed nutrients, and the bewitch of luminal contents as feces. While not an organ essential for life, the colon still plays a major mathematical function in maintaining the overall health of the human body. pinch these physiologic principles is integral to the happy treatment both medical checkup and surgical of colonic disease. Embryology The embryology of the colon informs its anatomy. In the third and twenty-five percent weeks of gestation, the uninitiate intestine arises from the cephalocaudal and lateral folding of the dorsal jump of the endoderm-lined yolk sac, forming a straight tube situated posteriorly in the embryo.13 Although the mucosa originates from the endoderm of the yolk sac, the muscular wall, connector t issue, and serosa have a mesodermal etiology. 4 By the fourth week of gestation, the intestine tube develops into three straightforward regions: the foregut, midgut, and hindgut.4 The midgut begins immediately distal to the confluence of the ballpark bile chamfer and the duodenum, extending to include the proximal two-thirds of the cross(prenominal) colon.

At the midgut, the primitive intestine maintains its association to the yolk sac via the vitelline duct; failure of the vitelline duct to nullify eventual(prenominal)ly results in a Meckels diverticulum or a vitelline cyst or fistula.2,5 The hindgu t reaches from the distal third of the tran! sverse colon to the anal canal proximal to the dentate line. The midgut receives its vascular show from the superior(p) mesenteric artery and the hindgut from the inferior mesenteric artery.6 The colon gains its ultimate position by means of a series of rotations of the immature gut. During the 5th week of gestation, the midgut, particularly the future ileum, rapidly enlarges beyond the capacity of the abdominal cavity,...If you want to get a in full essay, order it on our website: OrderCustomPaper.com

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